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Journal of Clinical Pathology 2008;61:770-772; doi:10.1136/jcp.2007.054585
Copyright © 2008 by the BMJ Publishing Group Ltd & Association of Clinical Pathologists.

CASE REPORTS

Rare provisional entity: primary cutaneous aggressive epidermotropic CD8+ cytotoxic T-cell lymphoma in a young woman

J Csomor1,3, Á Bognár1, S Benedek2, J Sinkó3, S Fekete3, L Krenács4, A Matolcsy1 and L Reiniger1

1 1st Department of Pathology and Experimental Cancer Research, Faculty of Medicine, Semmelweis University, Budapest, Hungary
2 3rd Department of Internal Medicine, Faculty of Medicine, Semmelweis University, Budapest, Hungary
3 Szent László Hospital, Budapest, Hungary
4 Laboratory of Tumour Pathology and Molecular Diagnostics, Institute of Biotechnology, Bay Zoltan Foundation for Applied Research, Szeged, Hungary

Correspondence to:
Dr L Reiniger, 1st Department of Pathology and Experimental Cancer Research, Faculty of Medicine, Semmelweis University, H-1085 Budapest, Ülloi út 26, Hungary; lillareiniger{at}yahoo.com

Primary cutaneous aggressive epidermotropic CD8+ cytotoxic T-cell lymphoma is a rare and provisional entity, characterised by cutaneous involvement and aggressive clinical behaviour. The case is here presented of a young woman with concurrent cutaneous and systemic involvement. Despite multi-agent chemotherapy, only partial remission could be achieved, and the patient died from therapy-resistant respiratory and circulatory failure. This case report is intended to add to the data collected on this rare entity, with only about 20 cases as yet described.


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