Journal of Clinical Pathology 2008;61:138-139
CASE REPORTS
Salmonella typhimurium meningitis in an adult patient with AIDS
1 Department of Microbiological Pathology, Medunsa Campus, University of Limpopo, and the National Health Laboratory Services, Pretoria, South Africa
2 Department of Internal Medicine, Kalafong Hospital, Pretoria, South Africa
Correspondence to:
Dr Khine Swe Swe, Department of Microbiological Pathology, Medunsa Campus, University of Limpopo, PO Box 211, Medunsa, 0204, Pretoria, South Africa; Ksweswe2003{at}yahoo.com
Salmonella meningitis is an unusual complication of Salmonella sepsis and occurs mainly in children. A rare case of Salmonella typhimurium meningitis occurring in an adult HIV positive man who presented with a history of fever and diarrhoea is reported. On examination he was dehydrated, and had oral thrush, weakness of lower limbs and neck stiffness. A septic diagnostic screen was performed and he was commenced on empiric intravenous cefotaxime therapy for meningitis. S typhimurium was cultured from cerebrospinal fluid and blood culture specimens. It was non-lactose fermenting, oxidase negative, H2S positive and motile. Cefotaxime was continued for 14 days and the patient responded without neurological sequelae.
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