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Published Online First: 17 October 2006. doi:10.1136/jcp.2006.042994
Journal of Clinical Pathology 2007;60:458-465
Copyright © 2007 by the BMJ Publishing Group Ltd & Association of Clinical Pathologists.

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REVIEW

Best practice in primary care pathology: review 7

W S A Smellie1, J Forth2, S R S Smart3, M J Galloway4, W Irving5, D Bareford6, P O Collinson7, K G Kerr8, G Summerfield9, P J Carey10, Rubin Minhas11

1 Department of Chemical Pathology, Bishop Auckland General Hospital, Cockton Hill Road, Bishop Auckland, County Durham, UK
2 Sowerby Centre for Health Informatics, Bede House, All Saints Business Centre, Newcastle upon Tyne, UK
3 PRODIGY Sowerby Centre for Health Informatics at Newcastle, Bede House, All Saints Business Centre, Newcastle upon Tyne, UK
4 Department of Haematology, City Hospitals Sunderland NHS Foundation Trust, Sunderland Royal Hospital, Kayll Road, Sunderland, UK
5 Department of Microbiology, School of Molecular Medical Sciences, University Hospital, Queen’s Medical Centre, Nottingham, UK
6 Department of Haematology, Russells Hall Hospital, Dudley, West Midlands, UK
7 Department of Chemical Pathology, Jenner Wing, St George’s Hospital, London, UK
8 Department of Microbiology, Harrogate District Hospital, Harrogate, North Yorkshire, UK
9 Department of Haematology, Queen Elizabeth Hospital, Gateshead, UK
10 Department of Haematology, Royal Victoria Infirmary, Newcastle upon Tyne, UK
11 Medway PCT Unit 2, Ambley Green, Bailey Drive, Gillingham Business Park, Kent, UK

Correspondence to:
Dr W S A Smellie
Department of Chemical Pathology, Bishop Auckland General Hospital, Cockton Hill Road, Bishop Auckland County, Durham DL14 6AD, UK; info{at}smellie.com
ABSTRACT
This seventh best-practice review examines four series of common primary care questions in laboratory medicine: (1) blood count abnormalities 2; (2) cardiac troponins; (3) high-density lipoprotein cholesterol; and (4) viral diseases 2. The review is presented in a question–answer format, with authorship attributed for each question series. The recommendations are a précis of guidance found using a standardised literature search of national and international guidance notes, consensus statements, health policy documents and evidence-based medicine reviews, supplemented by Medline Embase searches to identify relevant primary research documents. The recommendations are not standards, but form a guide to be set in the clinical context. Most are consensus based rather than evidence based. They will be updated periodically to take account of new information.


Abbreviations: ACS, acute coronary syndrome; CHD, coronary heart disease; CLL, chronic lymphocytic leukaemia; CMV, cytomegalovirus; EBV, Epstein–Barr virus; FBC, full blood count; GMS, General Medical Services; HDL-C, high-density lipoprotein cholesterol; LDL-C, low-density lipoprotein cholesterol




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