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Published Online First: 23 June 2006. doi:10.1136/jcp.2006.038604
Journal of Clinical Pathology 2007;60:244-250
Copyright © 2007 by the BMJ Publishing Group Ltd & Association of Clinical Pathologists.

VIEWPOINT

Our approach to follicular-patterned lesions of the thyroid

Zubair W Baloch and Virginia A LiVolsi

Department of Pathology and Laboratory Medicine, University of Pennsylvania Medical Center, Philadelphia, Pennsylvania, USA

Correspondence to:
Correspondence to:
Dr V A LiVolsi
Department of Pathology and Laboratory Medicine, 6 Founders Pavilion, 3400 Spruce Street, University of Pennsylvania Medical Center, Philadelphia, PA 19104, USA; linus{at}mail.med.upenn.edu

ABSTRACT

Follicular-patterned lesions of the thyroid are common; these include hyperplastic/adenomatoid nodules, follicular adenoma, follicular carcinoma and follicular variants of papillary carcinoma. Most of these lesions can be diagnosed with ease; however, there is a controversial subgroup. In this review, we present our diagnostic approach based on our experience with the histological diagnosis of these tumours, which can help in appropriate clinical management.

Abbreviations: FNA, fine needle aspirate; FVPTC, follicular variant of papillary thyroid carcinoma; PPAR, peroxisome proliferator-activated receptor; PTC papillary thyroid carcinoma


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