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Children’s vaccines do not induce cross reactivity against SARS-CoV

¹ State Key Laboratory for Agro-Biotechnology, College of Biological Science, China Agricultural University, Beijing, China
² Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan, Hubei, China

Correspondence to:
Dr B Wang
State Key Laboratory for Agro-Biotechnology, College of Biological Science, China Agricultural University, 2 Yuanmingyuan Xi Road, Beijing 100094, China; bwang3{at}cau.edu.cn
ABSTRACT
In contrast with adults, children infected by severe acute respiratory syndrome-corona virus (SARS-CoV) develop milder clinical symptoms. Because of this, it is speculated that children vaccinated with various childhood vaccines might develop cross immunity against SARS-CoV. Antisera and T cells from mice immunised with various vaccines were used to determine whether they developed cross reactivity against SARS-CoV. The results showed no marked cross reactivity against SARS-CoV, which implies that the reduced symptoms among children infected by SARS-CoV may be caused by other factors.