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Journal of Clinical Pathology 2007;60:204-205; doi:10.1136/jcp.2005.035808
Copyright © 2007 by the BMJ Publishing Group Ltd & Association of Clinical Pathologists.

CASE REPORT

Oral phaeohyphomycosis

S V Cardoso1,2, S S Campolina2, A L S Guimarães3, P R Faria4, E M da C Costa4, R S Gomez3, A Rocha5, R B Caligiorne2 and A M Loyola4

1 Oral Diagnosis Unit, State University of Montes Claros, Montes Claros, Brazil
2 Clinical Researches Laboratory, René Rachou Research Centre / FIOCRUZ, and Santa Casa de Misericórdia de Belo Horizonte Hospital, Minas Gerais, Brazil
3 Oral Pathology Department, Federal University of Minas Gerais, Minas Gerais, Brazil
4 Oral Pathology Unit, Federal University of Uberlândia, Uberlândia, Brazil
5 Surgical Pathology Department, Federal University of Uberlândia, Uberlandia, Brazil

Correspondence to:
Correspondence to:
Professor A M Loyola
Laboratório de Patologia Bucal, Universidade Federal de Uberlândia, Av Pará, 1720, Bloco 2U, CEP 38401-036, Uberlândia, MG/Brazil; adrianol{at}hc.ufu.br

ABSTRACT

This is the first description of solitary phaeohyphomycosis affecting the mucosal surface. The lesion developed in the inferior lip of a 57-year-old woman. After surgical resection, histopathological examination evidenced characteristic brownish fungal structures within granulomatous–purulent inflammation. Amplification and sequencing of rDNA obtained from paraffin-embedded tissue identified Alternaria species, as the causative agent.

Abbreviations: PCR, polymerase chain reaction


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