CASE REPORT
Russell body gastritis associated with Helicobacter pylori infection: a case report
1 Department of Diagnostic Pathology, Bundang Jesaeng General Hospital, Sungnam-si, Kyungki-do, Korea
2 Department of Pathology, Yonsei University College of Medicine, Seoul, Korea
3 Department of Internal Medicine, Institute of Gastroenterology, Yonsei University College of Medicine, Seoul, Korea
Correspondence to:
Correspondence to:
Y C Lee
Department of Internal Medicine, Yonsei University College of Medicine, 134, Shinchon-dong, Seodaemun-gu, Seoul 120-752, Korea; leeyc{at}yumc.yonsei.ac.kr
An unusual and rare gastric mucosal lesion histologically consisting of a localised accumulation of Russell bodies and Russell body-containing plasma cells, the so-called Mott cells, has been recognised only recently and termed as "Russell body gastritis". This lesion, despite its densely monomorphous appearance is easily confirmed to be non-neoplastic by its polyclonal immunoreactive pattern to immunoglobulin light chains. However, the aetiology of Russell body gastritis is controversial and hence the optimal treatment for this disease has not been established. Two cases of Russell body gastritis associated with Helicobacter pylori infection are reported, and the possible role of H pylori infection in the pathogenesis is discussed.
Abbreviations: lg, immunoglobulin; MALT, mucosa-associated lymphoid tissue
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