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Journal of Clinical Pathology 2006;59:1309-1311; doi:10.1136/jcp.2005.034991
Copyright © 2006 by the BMJ Publishing Group Ltd & Association of Clinical Pathologists.

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Medline Plus Health Information
*Kidney Transplantation
*Pancreas Transplantation
*Skin Cancer

CASE REPORT

Squamous cell carcinoma with rhabdoid phenotype and osteoclast-like giant cells in a renal–pancreas transplant recipient

K Aljerian, K O Alsaad, R Chetty, D Ghazarian

Department of Laboratory Medicine and Pathobiology, University of Toronto, University Health Network, Toronto, Ontario, Canada

Correspondence to:
D Ghazarian
University Health Network, Princess Margaret Hospital, 610 University Avenue, Toronto, ON M5G 2M9, Canada; danny.ghazarian{at}uhn.on.ca
ABSTRACT
Squamous cell carcinoma (SCC) is the commonest non-melanotic malignant skin tumour encountered after solid-organ transplantation. In this setting it is associated with a worse prognosis than sun-damage-induced SCC. Rhabdoid cells and osteoclastic giant cells are infrequently seen in SCC. This case highlights the unusual occurrence of rhabdoid cells and osteoclastic giant cells in a post-transplant SCC.


Abbreviations: OGC, osteoclast-like giant cell; SCC, squamous cell carcinoma







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Copyright © 2006 by the BMJ Publishing Group Ltd & Association of Clinical Pathologists.