JCP

HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS REGISTER
[Advanced]

Journal of Clinical Pathology 2006;59:1094-1096; doi:10.1136/jcp.2005.029017
Copyright © 2006 by the BMJ Publishing Group Ltd & Association of Clinical Pathologists.

This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when eLetters are posted
Right arrow Alert me if a correction is posted
Services
Right arrow Email this link to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Add article to my folders
Right arrow Download to citation manager
Right arrowRequest Permissions
Citing Articles
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Alwaheeb, S
Right arrow Articles by Asa, S L
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Alwaheeb, S
Right arrow Articles by Asa, S L

CASE REPORT

Worrisome histologic alterations following fine-needle aspiration of the parathyroid

S Alwaheeb1, G Rambaldini2, S Boerner1, C Coiré3, J Fiser4, S L Asa1

1 Department of Laboratory Medicine and Pathobiology, University of Toronto, University Health Network and Toronto Medical Laboratories, Toronto, Canada
2 Department of Medicine (Endocrinology), University of Toronto
3 Department of Laboratory Medicine, Trillium Health Centre, Mississauga, Ontario
4 Department of Pathology, Lakeridge Health Centre, Oshawa, Ontario

Correspondence to:
Dr S L Asa
Department of Laboratory Medicine and Pathobiology, University of Toronto, University Health Network and Toronto Medical Laboratories, 200 Elizabeth Street, 11th Floor, Toronto, Ontario M5G 2C4, Canada; sylvia.asa{at}uhn.on.ca
ABSTRACT
Fine-needle aspiration (FNA) is a procedure that is increasingly being performed. Artefacts occurring after FNA are reported to complicate the histological analysis of the tissue, mainly in the thyroid; WHAFFT (worrisome histologic alterations following FNA of thyroid) is well documented in the literature. The case of a male patient with hypercalcaemia who was subsequently found to have a nodule in the thyroid gland is reported here. He underwent FNA, followed by a total thyroidectomy and parathyroidectomy. The abnormality in the parathyroid gland showed worrisome histological changes that were suspicious of a malignant lesion, resembling the changes seen in the thyroid gland after FNA. Parathyroid cells were identified by a review of the previous FNA. The concept of WHAFFT, which can mimic the features of malignancy in the parathyroid gland, is therefore introduced.


Abbreviations: FNA, fine-needle aspiration; WHAFFT, worrisome histologic alterations following FNA of thyroid







HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS REGISTER
Journal of Clinical Pathology Molecular Pathology
Terms and conditions relating to subscriptions purchased online  ¦  Website terms and conditions  ¦  Privacy policy
Copyright © 2006 by the BMJ Publishing Group Ltd & Association of Clinical Pathologists.