ORIGINAL ARTICLE

A novel wavelet neural network based pathological stage detection technique for an oral precancerous condition

R R Paul¹, A Mukherjee², P K Dutta³, S Banerjee⁴, M Pal⁵, J Chatterjee⁶, K Chaudhuri⁷ and K Mukkerjee⁸

¹ Department of Oral and Maxillofacial Pathology, R Ahmed Dental College and Hospital, Kolkata, 700 014, India
² Centre of Excellence for Embedded Systems, Tata Consultancy Services, Kolkata, 700 091, India
³ Department of Electrical Engineering, Indian Institute of Technology, Kharagpur, 721 302 West Bengal, India
⁴ Department of Electronics and Electrical Communication Engineering, Indian Institute of Technology, Kharagpur, 721 302, India
⁵ Institute of Interdisciplinary Scientific Research, Kolkata, 700 005, West Bengal, India
⁶ Department of Radiology (Diagnosis) Medical College Hospitals, Kolkata, 700 073, India
⁷ Human Genetics and Genomics Group, Indian Institute of Chemical Biology, Kolkata, 700 032, India
⁸ Indian Institute of Chemical Biology

Correspondence to:
Correspondence to:
Dr K Chaudhuri
Human Genetics and Genomics Group, Indian Institute of Chemical Biology, 4, Raja S C Mullick Road, Kolkata-700032, India; kchaudhuri{at}iicb.res.in

Aim: To describe a novel neural network based oral precancer (oral submucous fibrosis; OSF) stage detection method.

Method: The wavelet coefficients of transmission electron microscopy images of collagen fibres from normal oral submucosa and OSF tissues were used to choose the feature vector which, in turn, was used to train the artificial neural network.

Results: The trained network was able to classify normal and oral precancer stages (less advanced and advanced) after obtaining the image as an input.

Conclusions: The results obtained from this proposed technique were promising and suggest that with further optimisation this method could be used to detect and stage OSF, and could be adapted for other conditions.

Abbreviations: ANN, artificial neural network; CAD, computer aided diagnosis; CWT, continuous wavelet transform; DWT, discrete wavelet transform; IID, interincisal distance; OSF, oral submucous fibrosis; PCBI, properly classified block index; TEM, transmission electron microscopy

Keywords: oral precancer; oral submucous fibrosis; collagen; transmission electron microscopy; image analysis; wavelet; artificial neural network

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