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Journal of Clinical Pathology 2005;58:1334-1335; doi:10.1136/jcp.2005.027300
Copyright © 2005 by the BMJ Publishing Group Ltd & Association of Clinical Pathologists.

CASE REPORT

Sclerochoroidal calcification associated with Gitelman syndrome and calcium pyrophosphate dihydrate deposition

R Gupta1, V Hu2, T Reynolds2 and R Harrison2

1 Birmingham and Midland Eye Centre, City Hospital NHS Trust, Dudley Road, Birmingham B18 7QU, UK
2 Queens Hospital, Belvedere Road, Burton upon Trent, Staffordshire, DE13 0RB, UK

Correspondence to:
Correspondence to:
MrR Gupta
Birmingham and Midland Eye Centre, City Hospital NHS Trust, Dudley Road, Birmingham B18 7QU, UK; rajen.gupta1{at}btinternet.com

ABSTRACT

Sclerochoroidal calcification is an uncommon condition. Metabolic evaluation and clinical examination are important to exclude associated systemic conditions such as the Bartter and Gitelman syndromes. It has been suggested that the lesions seen in sclerochoroidal calcification are calcium pyrophosphate dihydrate crystals. This report describes the first documented case in the UK of sclerochoroidal calcification associated with Gitelman syndrome and calcium pyrophosphate dihydrate deposition.

Abbreviations: CPPD, calcium pyrophosphate dihydrate; RPE, subretinal pigment epithelium

Keywords: calcium pyrophosphate dihydrate; deposition; sclerochoroidal calcification; Gitelman syndrome; hypokalaemia


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