© 2004 BMJ Publishing Group Ltd & Association of Clinical Pathologists
CASE REPORT
Endometrial coccidiosis
1 Department of Pathology, Hospital Txagorritxu, 01010 Alava, Spain
2 University of Tarragona, 43006 Tarragona, Spain
3 University Hospital, 18012 Granada, Spain
Correspondence to:
Correspondence to:
Dr F F Nogales
Departamento de Anatomía Patológica, Facultad de Medicina, 18012 Granada, Spain; fnogales{at}ugr.es
This report describes a case of granulomatous endometritis caused by coccidiosis in an immunologically uncompromised 63 year old patient. The glandular epithelium of the endometrium contained numerous intracytoplasmic cysts, corresponding to periodic acid Schiff positive and methenamine silver negative sporoblasts. The endometrial glands revealed reactive phenomena, such as eosinophilic and squamous glandular metaplasia and intraluminal desquamation. Non-necrotising epithelioid granulomata, lacking the presence of parasites, were present in the stroma. Although not detected in the stool examination, the organisms were probably Isospora belli. There was no evidence of other foci of the disease. Coccidiosis should be differentiated from the more commonly occurring coccidiomycosis.
Keywords: endometritis; granuloma; coccidiosis; coccidiomycosis; sporoblasts; eosinophilic metaplasia
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