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Angiosarcoma arising from skeletal haemangiomatosis in an atomic bomb survivor

Department of Orthopaedic Surgery, Kobe University School of Medicine, 7-5-1 Kusunoki-cho, Chuo-ku, Kobe 650-0017, Japan
Department of Pathology, Kobe University School of Medicine

Dr Yamamoto yamatetu{at}med.kobe-u.ac.jp The authors report a unique case in which an angiosarcoma arose from skeletal haemangiomatosis in a 72 year old man. This patient had a history of atomic bomb irradiation more than 50 years ago. Radiographically, the patient had multiple sclerotic foci of benign haemangiomas in the pelvis, the sacrum, and the left femur. The patient developed a high grade angiosarcoma in the left pubic bone. It is thought that atomic bomb irradiation played an important role in the development of the malignant lesion.

Key Words: angiosarcoma • haemangioma • atomic bomb