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Antithrombin III deficiency and cerebrovascular accidents in young adults.

Department of Haematology, Royal Cornwall Hospital, Treliske, Truro.

A young man with antithrombin III (AT-III) deficiency sustained a cerebellar venous infarct and recovered following treatment with AT-III concentrate. A family study showed that other members were affected. AT-III deficiency in this family was found to be due to a new variant AT-III TRURO 1. Young patients with strokes should be screened for thrombophilia.

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