Prevalence and intraoral distribution of Candida albicans in Sjögren's syndrome.

L Tapper-Jones, M Aldred, D M Walker

An imprint culture technique has been employed to study the prevalence and intraoral distribution of Candida albicans in 16 patients with Sjögren's syndrome and in 16 healthy controls matched for age, sex, and dental status. The prevalence and intraoral density of C. albicans was found to be significantly higher at almost all sites in the Sjögren's patients than in the controls. The distribution of candida was also altered, being significantly higher in the floor of the mouth and anterior labial sulcus in the Sjögren's group. There was an approximate inverse relationship between candida populations and rate of salivary flow. Mean candida densities were found to be significantly higher in those Sjögren's patients with detectable serum rheumatoid factor in the serum. However, patients with primary Sjögren's syndrome had significantly higher mean candida densities compared with patients with secondary Sjögren's syndrome.

CiteULike    Complore    Connotea    Del.icio.us    Digg    Reddit    Technorati    What's this?

This article has been cited by other articles:

• Mathews, S.A., Kurien, B.T., Scofield, R.H. (2008). Oral Manifestations of Sjogren's Syndrome. JDR 87: 308-318 [Abstract] [Full Text]  
• Samaranayake, Y. H., Samaranayake, L. P. (2001). Experimental Oral Candidiasis in Animal Models. Clin. Microbiol. Rev. 14: 398-429 [Abstract] [Full Text]  
• van der Reijden, W. A, Vissink, A., Veerman, E. C I, Amerongen, A. V N. (1999). Treatment of oral dryness related complaints (xerostomia) in Sjogren's syndrome. Ann Rheum Dis 58: 465-474 [Full Text]  
• Radford, D.R., Challacombe, S., Walter, J.D. (1999). Denture Plaque and Adherence of Candida Albicans To Denture-Base Materials in Vivo and in Vitro. CROBM 10: 99-116 [Abstract] [Full Text]  
• Scully, C., EI-Kabir, M., Samaranayake, L. P. (1994). Candida and Oral Candidosis: A Review. CROBM 5: 125-157 [Abstract] [Full Text]  
• Steller, M., Chou, L., Daniels, T.E. (1988). Electrical Stimulation of Salivary Flow in Patients with Sjogren's Syndrome. JDR 67: 1334-1337 [Abstract]  
• Parvinen, T., Larmas, M. (1981). The Relation of Stimulated Salivary Flow Rate and pH to Lactobacillus and Yeast Concentrations in Saliva. JDR 60: 1929-1935 [Abstract]